Brest nearing the drop after Rennes seal victory at the Stade Francis Le Ble.
Brest slipped closer to Ligue 2 after Rennes ran out two goal winners at the Stade Francis-Le Ble.
The rest left the hosts five points from safety, with four games to play, while 17th-placed Evian have a game in hand.
A debut goal from Abdoulaye Doucouré and first goal of the season from Víctor Montaño saw Rennes turn around their woeful run of form, and jump to tenth in Ligue 1.
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